Central nervous system depressant activity of Russelia equisetiformis

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Central nervous system depressant activity of Russelia equisetiformis.

The central nervous system depressant activity of the crude methanol extract (REC) and fractions (RE1, RE2, and RE3) of Russelia equisetiformis were evaluated in mice using the following models: amphetamine-induced stereotypy, picrotoxin-induced convulsion and phenobarbitone sleeping time. At 200-400 mg/kg, REC significantly increased phenobarbitone-sleeping time [P < 0.05] in a dose- dependent...

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ژورنال

عنوان ژورنال: Nigerian Journal of Physiological Sciences

سال: 2010

ISSN: 0794-859X

DOI: 10.4314/njps.v22i1-2.54871